Marini A, Grether-beck S, Jaenicke T, et al. Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women. Skin Pharmacol Physiol.There are conditions such as anemia, malabsorption syndromes, poor nutrition, vitamin deficiencies, hypothyroidism, and certain metabolic syndromes that can also lead to dark under-eye circles, Tirgari says. A less likely cause of dark circles is an underlying health condition. Phytochemical and therapeutic potential of cucumber. Youve Got an Underlying Medical Condition. Mukherjee, Pulok & Nema, Neelesh & Maity, Niladri & Sarkar, Birendra.American College of Allergy, Asthma, and Immunology.Infraorbital dark circles: A review of the pathogenesis, evaluation and treatment. J Cutan Aesthet Surg. Evaluation of the clinical efficacy and safety of an eye counter pad containing caffeine and vitamin K in emulsified Emu oil base. Ahmadraji, Fatemeh & Shatalebi, Mohammad.Periorbital hyperpigmentation: A comprehensive review. Sarkar R, Ranjan R, Garg S, Garg VK, Sonthalia S, Bansal S.
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